NCDR Provides Data for Recent Research Studies

Data from the American College of Cardiology's NCDR was the source of several studies published and presented in recent months, including studies examining use of guideline-recommended therapies in hypertension, statin therapy, and atrial fibrillation (AFib), as well as disparities in AFib treatment among American Indian/Alaskan Native patients and TAVR in cardiogenic shock patients.

PINNACLE Registry Studies Examine Use of Guideline-Recommended Therapies; Clinician Experience, Guideline Adherence
Recent research using data from ACC and Veradigm's PINNACLE Registry highlighted the association between guideline-recommended care and medication use for apparent treatment-resistant hypertension; statin therapy, stratified by patient income; and anticoagulation in patients with AFib and heart failure. Another study compared clinician experience and adherence to guideline-recommended care. Read more.

DOAC Switch Uncommon For AFib Patients Taking Warfarin, PINNACLE Study Finds
It is relatively uncommon for patients with AFib taking warfarin who are eligible to switch to a direct oral anticoagulant (DOAC) to do so, with about 1 in 6 switching to a DOAC between 2010 and 2016, according to a study published May 6 in Clinical Cardiology. Christopher T. Sciria, MD, et al used data from ACC and Veradigm's PINNACLE Registry to examine patterns of anticoagulation among AFib patients receiving warfarin and determine predictors of switching to DOACs. Read more.

NCDR Study Finds Disparities in AFib Treatment Among American Indian/Alaskan Native Patients
American Indian/Alaskan Native (AI/AN) patients with AFib are less likely than non-AI/AN patients to receive oral anticoagulation or rhythm control strategies, according to a study published May 25 in the Journal of the American College of Cardiology. Umair Khalid, MD, et al used data from ACC and Veradigm's PINNACLE Registry to compare baseline characteristics and treatment strategies among AI/AN patients with AFib to those among non-AI/AN patients. Read more.

PCI Procedures in Heart Transplant Patients Often Rarely Appropriate Under AUC, NCDR Study Finds
Most PCI procedures performed in heart transplant recipients may be considered rarely appropriate (RA) under appropriate use criteria for revascularization, according to a study recently published in JAMA Cardiology. Joe X. Xie, MD, MSCR, et al used data from ACC's CathPCI Registry to determine the rate of RA PCI procedures in heart transplant recipients vs nonrecipients and assess the relationship between rate of RA PCI procedures and hospital PCI appropriateness metrics and pay-for-performance scorecards. Read more.

NCDR Study Finds Moderate Correlation Between Procedure, Disease-Based Mortality
Among hospitals treating patients with acute myocardial infarction (AMI) and performing PCI, there may be a moderate correlation between procedural and disease-based outcomes, according to a study recently published in JAMA Cardiology. Ashwin S. Nathan, MD, et al used data from ACC's CathPCI Registry and Chest Pain - MI Registry to assess hospital-level correlations between disease-based AMI mortality and PCI procedural mortality among AMI patients at hospitals participating in both registries. The researchers also looked at whether hospital performance would be reclassified based on disease-based mortality vs procedural mortality. Read more.

NCDR Study: Lower One-Year MI, Revascularization in PCI of LIMA vs Other Graft Types
Patients undergoing PCI of the left internal mammary artery (LIMA) may have lower rates of recurrent myocardial infarction and repeat revascularization after one year, compared with those undergoing PCI of other arteries, according to a study published May 30 in the Journal of Invasive Cardiology. Using data from ACC's CathPCI Registry, Khung-Keong Yeo, MBBS, FACC, et al linked more than 1 million patient records to claims data from the Centers for Medicare and Medicaid Services to compare outcomes of PCI of the LIMA graft vs different bypass grafts to the left anterior descending coronary artery. Read more.

TAVR Viable Option For Patients With Cardiogenic Shock, Despite Increased Mortality
TAVR may be a viable option for patients with aortic stenosis (AS) presenting with acute cardiogenic shock, according to a study published June 1 in JACC: Cardiovascular Interventions. Luke Masha, MD, MPH, FACC, et al linked data from the STS/ACC TVT Registry with claims data from the Centers for Medicare and Medicaid Services to identify Medicare fee-for-service patients with AS who presented with cardiogenic shock before TAVR. The researchers compared this group to a cohort of high-risk patients who did not have cardiogenic shock before undergoing TAVR. The study's primary outcome was 30-day mortality following TAVR. Secondary outcomes included 30-day complications after TAVR. Read more.

No Differences in Lead Failure in Most Common ICD Leads: NCDR Post-Market Surveillance Study
Among the four most common ICD leads, there are no clinically significant differences in high-energy lead failure, according to a study recently published in Circulation: Cardiovascular Quality and Outcomes. In a post-market surveillance study, Frederic S. Resnic, MD, MSc, FACC, et al used data from ACC's ICD Registry to assess the comparative long-term safety of the four most commonly used ICD leads. The study's primary safety outcome was survival without lead failure for any reason, based on ICD Registry records of a subsequent procedure to remove and/or replace the original lead. Read more.

NCDR data and news was also previously highlighted. Read more:


The American College of Cardiology envisions a world where innovation and knowledge optimize cardiovascular care and outcomes. As the professional home for the entire cardiovascular care team, the mission of the College and its 54,000 members is to transform cardiovascular care and to improve heart health. The ACC bestows credentials upon cardiovascular professionals who meet stringent qualifications and leads in the formation of health policy, standards and guidelines. The College also provides professional medical education, disseminates cardiovascular research through its world-renowned JACC Journals, operates national registries to measure and improve care, and offers cardiovascular accreditation to hospitals and institutions. For more, visit acc.org.